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2023 | OriginalPaper | Chapter

ZnO-NPs-Coated Implants with Osteogenic Properties for Enhanced Osseointegration

Authors : Kate E. Mokobia, Ikhazuagbe H. Ifijen, Esther U. Ikhuoria

Published in: TMS 2023 152nd Annual Meeting & Exhibition Supplemental Proceedings

Publisher: Springer Nature Switzerland

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Abstract

The failure of orthopedic implants due to prosthesis-associated infections and aseptic loosening emphasizes the pressing need to enhance their antibacterial capacity and osseointegration. The biomedical field has extensively studied zinc oxide nanoparticles (ZnO-NPs). ZnO-NP-coated implants have drawn a lot of interest for their increased osseointegration due to their low toxicity, biocompatibility, high selectivity, good biological functions, and antibacterial and osteogenic properties. The use of ZnO-NPs in covering implants for better osseointegration has undergone significant advances, which were examined in this review. According to studies, ZnO-NPs coating on metal surfaces enhanced osteogenesis and soft tissue integration, which improved implant fixation. Additionally, osteoconductive nanoparticles create a chemical interaction with bone in order to achieve a strong biological attachment for implants. Implants with ZnO-NPs applied to their surfaces have a lower risk of infection, which unquestionably leads to better clinical results.

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Literature
1.
go back to reference Omorogbe SO, Aigbodion AI, Ifijen HI, Ogbeide-Ihama N, Simo A, Ikhuoria EU (2020) Low temperature synthesis of super paramagnetic Fe3O4 morphologies tuned using oleic acid as crystal growth modifier. In: TMS 149th annual meeting & exhibition supplemental proceedings, pp 619–631 Omorogbe SO, Aigbodion AI, Ifijen HI, Ogbeide-Ihama N, Simo A, Ikhuoria EU (2020) Low temperature synthesis of super paramagnetic Fe3O4 morphologies tuned using oleic acid as crystal growth modifier. In: TMS 149th annual meeting & exhibition supplemental proceedings, pp 619–631
2.
go back to reference Characterization of sulphated cellulose nanocrystals as stabilizer for magnetite nanoparticles synthesis with improved magnetic properties. Nig J Mater Sci Eng 7(2): 23–31 Characterization of sulphated cellulose nanocrystals as stabilizer for magnetite nanoparticles synthesis with improved magnetic properties. Nig J Mater Sci Eng 7(2): 23–31
3.
go back to reference Ifijen IH, Ikhuoria EU, Maliki M, Otabor GO, Aigbodion AI (2022) Nanostructured materials: a review on its application in water treatment. In: The Minerals, Metals & Materials Society (eds) TMS 2022 151st annual meeting & exhibition supplemental proceedings. The minerals, metals & materials series. Springer, Cham, pp 1172–1180 Ifijen IH, Ikhuoria EU, Maliki M, Otabor GO, Aigbodion AI (2022) Nanostructured materials: a review on its application in water treatment. In: The Minerals, Metals & Materials Society (eds) TMS 2022 151st annual meeting & exhibition supplemental proceedings. The minerals, metals & materials series. Springer, Cham, pp 1172–1180
4.
go back to reference Ifijen IH, Aghedo ON, Odiachi IJ, Omorogbe SO, Olu EL, Onuguh IC (2022) Nanostructured graphene thin films: a brief review of their fabrication techniques and corrosion protective performance. In: The Minerals, Metals & Materials Society (eds) TMS 2022 151st annual meeting & exhibition supplemental proceedings. The minerals, metals & materials series. Springer, Cham, pp 366–377 Ifijen IH, Aghedo ON, Odiachi IJ, Omorogbe SO, Olu EL, Onuguh IC (2022) Nanostructured graphene thin films: a brief review of their fabrication techniques and corrosion protective performance. In: The Minerals, Metals & Materials Society (eds) TMS 2022 151st annual meeting & exhibition supplemental proceedings. The minerals, metals & materials series. Springer, Cham, pp 366–377
5.
go back to reference Ifijen IH, Maliki M, Omorogbe SO, Ibrahim SD (2022) Incorporation of metallic nanoparticles into alkyd resin: a review of their coating performance. In: The Minerals, Metals & Materials Society (eds) TMS 2022 151st annual meeting & exhibition supplemental proceedings. The minerals, metals & materials series. Springer, Cham, pp 338–349 Ifijen IH, Maliki M, Omorogbe SO, Ibrahim SD (2022) Incorporation of metallic nanoparticles into alkyd resin: a review of their coating performance. In: The Minerals, Metals & Materials Society (eds) TMS 2022 151st annual meeting & exhibition supplemental proceedings. The minerals, metals & materials series. Springer, Cham, pp 338–349
6.
go back to reference Omorogbe, SO, Ikhuoria SO, Ifijen IH, Simo A, Aigbodion AI, Maaza M (2019) Fabrication of monodispersed needle-sized hollow core polystyrene microspheres. In: The Minerals, Metals & Mater Soc (eds) TMS 2019 148th annual meeting & exhibition supplemental proceedings, pp 155–164 Omorogbe, SO, Ikhuoria SO, Ifijen IH, Simo A, Aigbodion AI, Maaza M (2019) Fabrication of monodispersed needle-sized hollow core polystyrene microspheres. In: The Minerals, Metals & Mater Soc (eds) TMS 2019 148th annual meeting & exhibition supplemental proceedings, pp 155–164
7.
go back to reference Ifijen IH, Ikhuoria EU (2019) Generation of highly ordered 3d vivid monochromatic coloured photonic crystal films using evaporative induced technique. Tanzania J Sci 45(3):439449 Ifijen IH, Ikhuoria EU (2019) Generation of highly ordered 3d vivid monochromatic coloured photonic crystal films using evaporative induced technique. Tanzania J Sci 45(3):439449
8.
go back to reference Ifijen IH, Ikhuoria EU (2020) Monodisperse polystyrene microspheres: studies on the effects of reaction parameters on particle diameter. Tanzania J Sci 46(1):19–30 Ifijen IH, Ikhuoria EU (2020) Monodisperse polystyrene microspheres: studies on the effects of reaction parameters on particle diameter. Tanzania J Sci 46(1):19–30
9.
go back to reference Ifijen IH, Ikhuoria EU, Omorogbe SO (2018) Correlative studies on the fabrication of poly (styrene-methyl-methacrylate-acrylic acid) colloidal crystal films. J Dispersion Sci Tech 40(7):1–8 Ifijen IH, Ikhuoria EU, Omorogbe SO (2018) Correlative studies on the fabrication of poly (styrene-methyl-methacrylate-acrylic acid) colloidal crystal films. J Dispersion Sci Tech 40(7):1–8
10.
go back to reference Ifijen IH, Ikhuoria EU, Omorogbe SO, Aigbodion AI (2019a) Ordered colloidal crystals fabrication and studies on the properties of poly (styrene-butyl acrylate-acrylic acid) and polystyrene latexes. In: Srivatsan T, Gupta M (eds) Nanocomposites VI: nanoscience and nanotechnology in advanced composites. The minerals, metals & materials series. Springer, Cham, pp 155–164 Ifijen IH, Ikhuoria EU, Omorogbe SO, Aigbodion AI (2019a) Ordered colloidal crystals fabrication and studies on the properties of poly (styrene-butyl acrylate-acrylic acid) and polystyrene latexes. In: Srivatsan T, Gupta M (eds) Nanocomposites VI: nanoscience and nanotechnology in advanced composites. The minerals, metals & materials series. Springer, Cham, pp 155–164
11.
go back to reference Ifijen IH, Maliki M, Ovonramwen OB, Aigbodion AI, Ikhuoria EU (2019) Brilliant coloured monochromatic photonic crystals films generation from poly (styrene-butyl acrylate-acrylic acid) latex. J Appl Sci Environ Mgt 23(9):1661–1664 Ifijen IH, Maliki M, Ovonramwen OB, Aigbodion AI, Ikhuoria EU (2019) Brilliant coloured monochromatic photonic crystals films generation from poly (styrene-butyl acrylate-acrylic acid) latex. J Appl Sci Environ Mgt 23(9):1661–1664
12.
go back to reference Ifijen IH, Omorogbe SO, Maliki M, Odiachi IJ, Aigbodion AI, Ikhuoria EU (2020) Stabilizing capability of gum Arabic on the synthesis of poly (styrene-methylmethacrylate-acrylic acid) latex for the generation of colloidal crystal films. Tanzania J Sci 46(2):345–435 Ifijen IH, Omorogbe SO, Maliki M, Odiachi IJ, Aigbodion AI, Ikhuoria EU (2020) Stabilizing capability of gum Arabic on the synthesis of poly (styrene-methylmethacrylate-acrylic acid) latex for the generation of colloidal crystal films. Tanzania J Sci 46(2):345–435
13.
go back to reference Omorogbe SO, Ikhuoria EU, Igiehon LI, Agbonlahor GO, Ifijen IH, Aigbodion AI (2017) Characterization of sulphated cellulose nanocrystals as stabilizer for magnetite nanoparticles synthesis with improved magnetic properties. Nigerian J Mater Sci Technol 7:21–30 Omorogbe SO, Ikhuoria EU, Igiehon LI, Agbonlahor GO, Ifijen IH, Aigbodion AI (2017) Characterization of sulphated cellulose nanocrystals as stabilizer for magnetite nanoparticles synthesis with improved magnetic properties. Nigerian J Mater Sci Technol 7:21–30
14.
go back to reference Ifijen IH, Maliki M, Odiachi IJ, Aghedo ON, Ohiocheoya EB (2022) Review on solvents-based alkyd resins and water borne alkyd resins: impacts of modification on their coating properties. Chem Afri 5:211–225CrossRef Ifijen IH, Maliki M, Odiachi IJ, Aghedo ON, Ohiocheoya EB (2022) Review on solvents-based alkyd resins and water borne alkyd resins: impacts of modification on their coating properties. Chem Afri 5:211–225CrossRef
15.
go back to reference Ifijen IH, Ikhuoria EU, Aigbodion AI, Omorogbe SO (2018) Impact of varying the concentration of tetraethyl-orthosilicate on the average particle diameter of monodisperse colloidal silica spheres. Chem Sci J 9(1):183–185 Ifijen IH, Ikhuoria EU, Aigbodion AI, Omorogbe SO (2018) Impact of varying the concentration of tetraethyl-orthosilicate on the average particle diameter of monodisperse colloidal silica spheres. Chem Sci J 9(1):183–185
16.
go back to reference Ikhuoria EU, Ifijen IH, Georgina OP, Ehigie AC, Omorogbe SO, Aigbodion AI (2020) The adsorption of heavy metals from aqueous solutions using silica microparticles synthesized from sodium silicate. Ni-Co 2021: The 5th International Symposium on Ni and Co, pp 195–205 Ikhuoria EU, Ifijen IH, Georgina OP, Ehigie AC, Omorogbe SO, Aigbodion AI (2020) The adsorption of heavy metals from aqueous solutions using silica microparticles synthesized from sodium silicate. Ni-Co 2021: The 5th International Symposium on Ni and Co, pp 195–205
17.
go back to reference Ifijen IH, Itua AB, Maliki M, Ize-Iyamu CO, Omorogbe SO, Aigbodion AI, Ikhuoria EU (2020) The removal of nickel and lead ions from aqueous solutions using green synthesized silica microparticles. Heliyon 6(9):e04907CrossRef Ifijen IH, Itua AB, Maliki M, Ize-Iyamu CO, Omorogbe SO, Aigbodion AI, Ikhuoria EU (2020) The removal of nickel and lead ions from aqueous solutions using green synthesized silica microparticles. Heliyon 6(9):e04907CrossRef
20.
go back to reference Mack D, Rohde H, Harris L, Davies A, Horstkotte M, Knobloch J (2006) Biofilm formation in medical device-related infection. Int J Artif Organs 29:343–402CrossRef Mack D, Rohde H, Harris L, Davies A, Horstkotte M, Knobloch J (2006) Biofilm formation in medical device-related infection. Int J Artif Organs 29:343–402CrossRef
21.
go back to reference Otto M (2013) Staphylococcal infections: mechanisms of biofilm maturation and detachment as critical determinants of pathogenicity. Annu Rev Med 64:175–188CrossRef Otto M (2013) Staphylococcal infections: mechanisms of biofilm maturation and detachment as critical determinants of pathogenicity. Annu Rev Med 64:175–188CrossRef
22.
go back to reference Aviv M, Berdicevsky I, Zilberman M (2007) Gentamicin-loaded bioresorbable films for prevention of bacterial infections associated with orthopedic implants. J Biomed Mater Res A 83:10–19CrossRef Aviv M, Berdicevsky I, Zilberman M (2007) Gentamicin-loaded bioresorbable films for prevention of bacterial infections associated with orthopedic implants. J Biomed Mater Res A 83:10–19CrossRef
23.
go back to reference Rai M, Yadav A, Gade A (2009) Silver nanoparticles as a new generation of antimicrobials. Biotechnol Adv 27:76–159CrossRef Rai M, Yadav A, Gade A (2009) Silver nanoparticles as a new generation of antimicrobials. Biotechnol Adv 27:76–159CrossRef
24.
go back to reference Pushpalatha C, Suresh J, Gayathri VS, Sowmya SV, Augustine D, Alamoudi A, Zidane B, Mohammad NH, Patil S (2022) Zinc oxide nanoparticles: a review on its applications in dentistry. Front Bioeng Biotechnol 10:917990CrossRef Pushpalatha C, Suresh J, Gayathri VS, Sowmya SV, Augustine D, Alamoudi A, Zidane B, Mohammad NH, Patil S (2022) Zinc oxide nanoparticles: a review on its applications in dentistry. Front Bioeng Biotechnol 10:917990CrossRef
25.
go back to reference Baek M, Chung H-E, Yu J, Lee J-A, Kim T-H, Oh J-M et al (2012) Int J Nanomedicine 7:3081 Baek M, Chung H-E, Yu J, Lee J-A, Kim T-H, Oh J-M et al (2012) Int J Nanomedicine 7:3081
26.
go back to reference Wang P, Li A, Yu L, Chen Y, Xu D (2020) Energy conversion-based nanotherapy for rheumatoid arthritis treatment. Front Bioeng Biotechnol 10(8):652CrossRef Wang P, Li A, Yu L, Chen Y, Xu D (2020) Energy conversion-based nanotherapy for rheumatoid arthritis treatment. Front Bioeng Biotechnol 10(8):652CrossRef
27.
go back to reference Miller MA, Zachary JF (2017) Mechanisms and morphology of cellular injury, adaptation, and death. Pathologic Basis Vet Dis 2–43:e19 Miller MA, Zachary JF (2017) Mechanisms and morphology of cellular injury, adaptation, and death. Pathologic Basis Vet Dis 2–43:e19
28.
go back to reference Moradpoor H, Safaei M, Mozaffari HR, Sharifi R, Imani MM, Golshah A, Bashardoust N (2021) An overview of recent progress in dental applications of zinc oxide nanoparticles. RSC Adv 11(34):21189–21206CrossRef Moradpoor H, Safaei M, Mozaffari HR, Sharifi R, Imani MM, Golshah A, Bashardoust N (2021) An overview of recent progress in dental applications of zinc oxide nanoparticles. RSC Adv 11(34):21189–21206CrossRef
29.
go back to reference Zhang T, Liu J, Fellner M, Zhang C, Sui D, Hu J (2017) Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway. Sci Adv 3(8):1700344CrossRef Zhang T, Liu J, Fellner M, Zhang C, Sui D, Hu J (2017) Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway. Sci Adv 3(8):1700344CrossRef
30.
go back to reference Choi S, Liu X, Pan Z (2018) Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases. Acta Pharmacol Sin 39(7):1120–1132CrossRef Choi S, Liu X, Pan Z (2018) Zinc deficiency and cellular oxidative stress: prognostic implications in cardiovascular diseases. Acta Pharmacol Sin 39(7):1120–1132CrossRef
31.
go back to reference Suh KS, Lee YS, Seo SH, Kim YS, Choi EM (2013) Effect of zinc oxide nanoparticles on the function of MC3T3-E1 osteoblastic cells. Biol Trace Elem Res 155(2):287–294CrossRef Suh KS, Lee YS, Seo SH, Kim YS, Choi EM (2013) Effect of zinc oxide nanoparticles on the function of MC3T3-E1 osteoblastic cells. Biol Trace Elem Res 155(2):287–294CrossRef
32.
go back to reference Chen J, Zhang X, Cai H, Chen Z, Wang T, Jia L, Wang J, Wan Q, Pei X (2016) Osteogenic activity and antibacterial effect of zinc oxide/carboxylated graphene oxide nanocomposites: preparation and in vitro evaluation. Colloids Surf B Biointerfaces 147:397–407CrossRef Chen J, Zhang X, Cai H, Chen Z, Wang T, Jia L, Wang J, Wan Q, Pei X (2016) Osteogenic activity and antibacterial effect of zinc oxide/carboxylated graphene oxide nanocomposites: preparation and in vitro evaluation. Colloids Surf B Biointerfaces 147:397–407CrossRef
33.
go back to reference Yamaguchi M, Weitzmann MN (2011) Zinc stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-kappaB activation. Mol Cell Biochem 355(1–2):179–186CrossRef Yamaguchi M, Weitzmann MN (2011) Zinc stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-kappaB activation. Mol Cell Biochem 355(1–2):179–186CrossRef
34.
go back to reference Park KH, Choi Y, Yoon DS, Lee KM, Kim D, Lee JW (2018) Zinc promotes osteoblast differentiation in human mesenchymal stem cells via activation of the cAMP-PKA-CREB signaling pathway. Stem Cells Dev 27(16):1125–1135CrossRef Park KH, Choi Y, Yoon DS, Lee KM, Kim D, Lee JW (2018) Zinc promotes osteoblast differentiation in human mesenchymal stem cells via activation of the cAMP-PKA-CREB signaling pathway. Stem Cells Dev 27(16):1125–1135CrossRef
35.
go back to reference Colon G, Ward BC, Webster TJ (2006) Increased osteoblast and decreased Staphylococcus epidermidis functions on nanophase ZnO and TiO2. J Biomed Mater Res A 78A(3):595–604CrossRef Colon G, Ward BC, Webster TJ (2006) Increased osteoblast and decreased Staphylococcus epidermidis functions on nanophase ZnO and TiO2. J Biomed Mater Res A 78A(3):595–604CrossRef
36.
go back to reference Li Y, Yang Y, Qing Y, Li R, Tang X, Guo D, Qin Y (2020) Enhancing ZnO-NP antibacterial and osteogenesis properties in orthopedic applications: a review. Int J Nanomed 15:6247–6262CrossRef Li Y, Yang Y, Qing Y, Li R, Tang X, Guo D, Qin Y (2020) Enhancing ZnO-NP antibacterial and osteogenesis properties in orthopedic applications: a review. Int J Nanomed 15:6247–6262CrossRef
37.
go back to reference Sahmani S, Saber-Samandari S, Shahali M, Yekta HJ, Aghadavoudi F, Montazeran AH, Aghdam MM, Khandan A (2018) Mechanical and biological performance of axially loaded novel bio-nanocomposite sandwich plate-type implant coated by biological polymer thin film. J Mech Behav Biomed Mater 88:238–250CrossRef Sahmani S, Saber-Samandari S, Shahali M, Yekta HJ, Aghadavoudi F, Montazeran AH, Aghdam MM, Khandan A (2018) Mechanical and biological performance of axially loaded novel bio-nanocomposite sandwich plate-type implant coated by biological polymer thin film. J Mech Behav Biomed Mater 88:238–250CrossRef
38.
go back to reference Li Y, Sun L, Webster TJ (2018) The investigation of ZnO/poly(vinylidene fluoride) nanocomposites with improved mechanical, piezoelectric, and antimicrobial properties for orthopedic applications. J Biomed Nanotechnol 14(3):536–545CrossRef Li Y, Sun L, Webster TJ (2018) The investigation of ZnO/poly(vinylidene fluoride) nanocomposites with improved mechanical, piezoelectric, and antimicrobial properties for orthopedic applications. J Biomed Nanotechnol 14(3):536–545CrossRef
39.
go back to reference Park JK, Kim YJ, Yeom J, Jeon JH, Yi GC, Je JH, Hahn SK (2010) The topographic effect of zinc oxide nanoflowers on osteoblast growth and osseointegration. Adv Mater 22(43):4857–4861CrossRef Park JK, Kim YJ, Yeom J, Jeon JH, Yi GC, Je JH, Hahn SK (2010) The topographic effect of zinc oxide nanoflowers on osteoblast growth and osseointegration. Adv Mater 22(43):4857–4861CrossRef
40.
go back to reference Lee J, Kang BS, Hicks B, Chancellor TF Jr, Chu BH, Wang HT, Keselowsky BG, Ren F, Lele TP (2008) The control of cell adhesion and viability by zinc oxide nanorods. Biomaterials 29(27):3743–3749CrossRef Lee J, Kang BS, Hicks B, Chancellor TF Jr, Chu BH, Wang HT, Keselowsky BG, Ren F, Lele TP (2008) The control of cell adhesion and viability by zinc oxide nanorods. Biomaterials 29(27):3743–3749CrossRef
41.
go back to reference Nebe JG, Luethen F, Lange R, Beck U (2007) Interface interactions of osteoblasts with structured titanium and the correlation between physicochemical characteristics and cell biological parameters. Macromol Biosci 7(5):567–578CrossRef Nebe JG, Luethen F, Lange R, Beck U (2007) Interface interactions of osteoblasts with structured titanium and the correlation between physicochemical characteristics and cell biological parameters. Macromol Biosci 7(5):567–578CrossRef
42.
go back to reference Memarzadeh K, Sharili AS, Huang J, Rawlinson SC, Allaker RP (2014) Nanoparticulate zinc oxide as a coating material for orthopedic and dental implants. J Biomed Mater Res A 103(3):981–989CrossRef Memarzadeh K, Sharili AS, Huang J, Rawlinson SC, Allaker RP (2014) Nanoparticulate zinc oxide as a coating material for orthopedic and dental implants. J Biomed Mater Res A 103(3):981–989CrossRef
43.
go back to reference Wang D, Cui L, Chang X, Guan D (2020) Biosynthesis and characterization of zinc oxide nanoparticles from Artemisia annua and gate their effect on proliferation, osteogenic differentiation and mineralization in human osteoblast-like MG-63 Cells. J Photochem Photobiol B 202:111652CrossRef Wang D, Cui L, Chang X, Guan D (2020) Biosynthesis and characterization of zinc oxide nanoparticles from Artemisia annua and gate their effect on proliferation, osteogenic differentiation and mineralization in human osteoblast-like MG-63 Cells. J Photochem Photobiol B 202:111652CrossRef
44.
go back to reference Shen X, Hu Y, Xu G et al (2014) Regulation of the biological functions of osteoblasts and bone formation by Zn-incorporated coating on microrough titanium. ACS Appl Mater Interfaces 6(18):16426–16440CrossRef Shen X, Hu Y, Xu G et al (2014) Regulation of the biological functions of osteoblasts and bone formation by Zn-incorporated coating on microrough titanium. ACS Appl Mater Interfaces 6(18):16426–16440CrossRef
45.
go back to reference Shitole AA, Raut PW, Sharma N, Giram P, Khandwekar AP, Garnaik B (2019) Electrospun polycaprolactone/hydroxyapatite/ZnO nanofibers as potential biomaterials for bone tissue regeneration. J Mater Sci Mater Med 30(5):51CrossRef Shitole AA, Raut PW, Sharma N, Giram P, Khandwekar AP, Garnaik B (2019) Electrospun polycaprolactone/hydroxyapatite/ZnO nanofibers as potential biomaterials for bone tissue regeneration. J Mater Sci Mater Med 30(5):51CrossRef
46.
go back to reference Maimaiti B, Zhang N, Yan L, Luo J, Xie C, Wang Y, Ma C, Ye T (2020) Stable ZnO-doped hydroxya patite nanocoating for anti-infection and osteogenic on titanium. Colloids Surf B Biointerf 186:110731CrossRef Maimaiti B, Zhang N, Yan L, Luo J, Xie C, Wang Y, Ma C, Ye T (2020) Stable ZnO-doped hydroxya patite nanocoating for anti-infection and osteogenic on titanium. Colloids Surf B Biointerf 186:110731CrossRef
47.
go back to reference Gnaneshwar PV, Sudakaran SV, Abisegapriyan S, Sherine J, Ramakrishna S, Rahim MHA, Yusoff MM, Venugopal RJJR (2019) Ramification of zinc oxide doped hydroxyapatite biocomposites for the mineralization of osteoblasts. Mater Sci Eng C Mater Biol Appl 96:337–346CrossRef Gnaneshwar PV, Sudakaran SV, Abisegapriyan S, Sherine J, Ramakrishna S, Rahim MHA, Yusoff MM, Venugopal RJJR (2019) Ramification of zinc oxide doped hydroxyapatite biocomposites for the mineralization of osteoblasts. Mater Sci Eng C Mater Biol Appl 96:337–346CrossRef
48.
go back to reference Kachoei M, Nourian A, Divband B, Kachoei Z, Shirazi S (2016) Zinc-oxide nanocoating for improvement of the antibacterial and frictional behavior of nickel-titanium alloy. Nanomedicine (Lond) 11(19):2511–2527CrossRef Kachoei M, Nourian A, Divband B, Kachoei Z, Shirazi S (2016) Zinc-oxide nanocoating for improvement of the antibacterial and frictional behavior of nickel-titanium alloy. Nanomedicine (Lond) 11(19):2511–2527CrossRef
49.
go back to reference Costa BC, Rodrigues EA, Tokuhara CK, Oliveira RC, Lisboa PN, Rocha LA (2018) ZnO nanoparticles with different sizes and morphologies for medical implant coatings: synthesis and cytotoxicity. Bio Nano Sci 8:587–595 Costa BC, Rodrigues EA, Tokuhara CK, Oliveira RC, Lisboa PN, Rocha LA (2018) ZnO nanoparticles with different sizes and morphologies for medical implant coatings: synthesis and cytotoxicity. Bio Nano Sci 8:587–595
50.
go back to reference Zhao Z, Wan Y, Yu M, Wang H, Cai Y, Liu C, Zhang D (2021) Biocompability evaluation of micro textures coated with zinc oxide onTi-6Al-4V treated by nanosecond laser. Surf Coatings Technol 422:127453ACrossRef Zhao Z, Wan Y, Yu M, Wang H, Cai Y, Liu C, Zhang D (2021) Biocompability evaluation of micro textures coated with zinc oxide onTi-6Al-4V treated by nanosecond laser. Surf Coatings Technol 422:127453ACrossRef
Metadata
Title
ZnO-NPs-Coated Implants with Osteogenic Properties for Enhanced Osseointegration
Authors
Kate E. Mokobia
Ikhazuagbe H. Ifijen
Esther U. Ikhuoria
Copyright Year
2023
DOI
https://doi.org/10.1007/978-3-031-22524-6_27

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