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Key Scientific Issues in Research for Quality Control of Chinese Medicines Read chapter Read first chapter

2024 | OriginalPaper | Chapter

15. HPLC and HPLC–MS for Qualitative and Quantitative Analysis of Chinese Medicines

Authors : You Qin, Shaoping Li, Jing Zhao

Published in: Quality Control of Chinese Medicines

Publisher: Springer Nature Singapore

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Abstract

Active compounds derived from Chinese medicines (CMs) have already illustrated immense therapeutic potential over an array of different diseases, and served as an inexhausted source for drug discovery and development. With the continuous development of the instrumentation’s capabilities as far as detection and separation is concerned, analytical methods for these components have come into the spotlight. Based on the extra sensitivity, specificity, and good separation in complex samples, HPLC and LC–MS have been the ultimate tool in the qualitative and quantitative tools for the determination of different types of chemical compounds. Herein, we focus on the achievements in qualitative and quantitative analysis of the major classes of phytochemicals (flavonoids, alkaloids, saponins, terpenoids, and carbohydrates) in CMs through HPLC and LC–MS.

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previous chapter Application of Gas Chromatography and Gas Chromatography–Mass Spectrometry in Quality Control of Chinese Medicines
next chapter Quality Control of Chinese Medicines Using UPLC–MS
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Metadata
Title
HPLC and HPLC–MS for Qualitative and Quantitative Analysis of Chinese Medicines
Authors
You Qin
Shaoping Li
Jing Zhao
Copyright Year
2024
Publisher
Springer Nature Singapore
Book
Quality Control of Chinese Medicines

Print ISBN: 978-981-9998-70-8

Electronic ISBN: 978-981-9998-71-5

Copyright Year: 2024

DOI
https://doi.org/10.1007/978-981-99-9871-5_15

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