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2024 | OriginalPaper | Chapter

16. Quality Control of Chinese Medicines Using UPLC–MS

Authors : Jia-Yi Zheng, Li-Fang Liu

Published in: Quality Control of Chinese Medicines

Publisher: Springer Nature Singapore

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Abstract

Quality control of Chinese medicines (CMs) is a difficult work because of their intrinsic complexity. UPLC-MS is at the forefront of this crucial challenge due to its prominent performance in qualitative and quantitative analysis. This chapter aims to explain UPLC-MS-based methodologies in the field of quality control for CMs, covering the basic principles of various instruments, and their specific applications in the characterization of chemical composition, screening, and quantification of chemical markers. Meanwhile, a description of some universal or integrated strategies (e.g., fingerprints, chemical markers’ knock-out, multivariate statistical analysis and quantitative analysis of multi-components by single marker) are also provided.

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Metadata
Title
Quality Control of Chinese Medicines Using UPLC–MS
Authors
Jia-Yi Zheng
Li-Fang Liu
Copyright Year
2024
Publisher
Springer Nature Singapore
DOI
https://doi.org/10.1007/978-981-99-9871-5_16

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